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Yoshifumi Jigami Selected Research

mannoproteins

1/2008[Biosynthetic pathway of GPI-anchored cell wall mannoproteins in yeast as a potential target for anti-fungal and anti-cancer drugs].
5/2003Medicinal genetics approach towards identifying the molecular target of a novel inhibitor of fungal cell wall assembly.

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Yoshifumi Jigami Research Topics

Disease

5Fabry Disease (Fabry's Disease)
02/2012 - 12/2002
3Lysosomal Storage Diseases (Lysosomal Storage Disease)
04/2011 - 08/2007
2GM2 Gangliosidoses (GM2 Gangliosidosis)
04/2011 - 08/2007
1Sandhoff Disease (Sandhoff's Disease)
04/2011
1Neurologic Manifestations (Neurological Manifestations)
04/2011
1Tay-Sachs Disease
04/2011
1Metabolic Diseases (Metabolic Disease)
04/2011
1Hypersensitivity (Allergy)
11/2009
1Neoplasms (Cancer)
01/2008
1Nervous System Diseases (Neurological Disorders)
08/2006
1Cicatrix (Scar)
11/2005
1Walker-Warburg Syndrome
01/2004
1Muscular Dystrophies (Muscular Dystrophy)
01/2004
1Group II Malformations of Cortical Development
01/2004
1Mycoses (Diseases, Fungus)
05/2003

Drug/Important Bio-Agent (IBA)

7EnzymesIBA
02/2012 - 12/2002
4Proteins (Proteins, Gene)FDA Link
11/2009 - 01/2004
3alpha-Galactosidase (Beano)IBA
01/2006 - 12/2002
2Polysaccharides (Glycans)IBA
02/2012 - 09/2009
2agalsidase alfaIBA
02/2012 - 01/2006
2Glycoproteins (Glycoprotein)IBA
02/2012 - 12/2002
2Mannose (D-Mannose)IBA
04/2011 - 01/2006
2mannoproteinsIBA
01/2008 - 05/2003
1GlycosphingolipidsIBA
02/2012
1Therapeutic UsesIBA
04/2011
1Hexosaminidase A (Hex A)IBA
04/2011
1Pharmaceutical PreparationsIBA
04/2011
1alpha-N-Acetylgalactosaminidase (N-Acetyl-alpha-D-Galactosaminidase)IBA
11/2009
1globotriaosylceramide (globotriosylceramide)IBA
11/2009
1GangliosidesIBA
08/2007
1G(M2) Ganglioside (Ganglioside GM2)IBA
08/2007
1agalsidase betaFDA Link
01/2006
1mannose-6-phosphateIBA
01/2006
1Bovine Serum AlbuminIBA
01/2006
1Red Fluorescent ProteinIBA
11/2005
1ChitinIBA
11/2005
1MannosyltransferasesIBA
01/2004
1Dystroglycans (Dystroglycan)IBA
01/2004
1protein O-mannosyltransferase (dolichyl-phosphate-mannose - protein mannosyltransferase)IBA
01/2004
1alpha-Mannosidase (LAMAN)IBA
12/2002
1SugarsIBA
12/2002

Therapy/Procedure

8Enzyme Replacement Therapy
02/2012 - 12/2002
1Therapeutics
12/2002